21-10-2022, 05:12 PM
I, being poor, have only my dreams; I have spread my dreams under your feet; Tread softly because you tread on my dreams.
![](https://i.imgur.com/CLvY2jA.png")
CNA : China cannot back down from Covid Zero - it is stuck forever
I, being poor, have only my dreams; I have spread my dreams under your feet; Tread softly because you tread on my dreams.
21-10-2022, 05:14 PM
If Xi backs down he lose face.
If he does not back down, economy weaken and people suffer.
Between the 2, for a dictator his face is always more important than the people.
If he does not back down, economy weaken and people suffer.
Between the 2, for a dictator his face is always more important than the people.
I, being poor, have only my dreams; I have spread my dreams under your feet; Tread softly because you tread on my dreams.
21-10-2022, 05:24 PM
(21-10-2022, 05:14 PM)sgbuffett Wrote: If Xi backs down he lose face.
If he does not back down, economy weaken and people suffer.
Between the 2, for a dictator his face is always more important than the people.
Robert Kelly (@Robert_E_Kelly) is a professor of international relations in the Department of Political Science at Pusan National University.
21-10-2022, 05:35 PM
(21-10-2022, 05:24 PM)cityhantam Wrote: Robert Kelly (@Robert_E_Kelly) is a professor of international relations in the Department of Political Science at Pusan National University.
Latest news claiming that China is now looking to shorten the quarantine period in entering China. There is nothing to do with whether President Xi is losing face or backing down but more about taking measures in protecting their Chinese citizens.
By far only China cares more about their citizens, compared to many western world who simply exposed the virus to many of their people. In some cases they have resulted many people’s death in the course of their opening up their borders.
Westerners simply don’t like to be single out to have “caused” their citizen’s death, they need to drag along China who has the largest population who has been holding up well in their death toll. Therefore these westerners have to paint the “devil” out of the China leadership.
https://www.zaobao.com.sg/realtime/china...20-1324681
![[+]](https://sgtalk.net/images/bootbb/collapse_collapsed.png)
21-10-2022, 05:39 PM
if you're taking care of 1.4b ppl, you cannot suka suka switch from extreme kiasee to extreme kiaboh, unlike some individuals
21-10-2022, 05:45 PM
Is ah butt willing to vouch that there will low death rate once China opens up?
21-10-2022, 06:46 PM
(21-10-2022, 05:14 PM)sgbuffett Wrote: If Xi backs down he lose face.
If he does not back down, economy weaken and people suffer.
Between the 2, for a dictator his face is always more important than the people.
US famous Harvard U did a ten years' study of support and popularity of Gov among the people in China, they found their support rate generally are between 80 to 95%.
Do you see such support and satisfaction in western govs like Biden, Truss and Macron?
Breakthrough Research Shows Growing Public Satisfaction with Chinese Government (asiapacific.ca)
![[Image: Gov01.png]](https://i.ibb.co/x57MmNj/Gov01.png)
Understanding CCP Resilience: Surveying Chinese Public Opinion Through Time | Ash Center (harvard.edu)
![[Image: Gov02.png]](https://i.ibb.co/F3vcJSH/Gov02.png)
21-10-2022, 07:36 PM
(21-10-2022, 05:39 PM)WhatDoYouThink! Wrote: if you're taking care of 1.4b ppl, you cannot suka suka switch from extreme kiasee to extreme kiaboh, unlike some individuals
That would represent a huge boost compared to traditional shots in the arm, which have proved very effective at preventing severe COVID-19 but perform far less well when it comes to stopping transmission.
Last month China became the first country to approve a needle-free COVID-19 vaccine, an aerosolised mist inhaled through the nose and mouth using a nebuliser device, while India greenlit a homegrown nasal drop vaccine days later.
With this could not block people from getting infected - and also potentially hamper those who have COVID-19 from spreading it further.
However, the vaccine promoted mucosal antibodies only in a minority of the participants, and the immune responses according to a study published in the journal eBioMedicine.
21-10-2022, 07:44 PM
(21-10-2022, 07:36 PM)Teeth53 Wrote: That would represent a huge boost compared to traditional shots in the arm, which have proved very effective at preventing severe COVID-19 but perform far less well when it comes to stopping transmission.
Last month China became the first country to approve a needle-free COVID-19 vaccine, an aerosolised mist inhaled through the nose and mouth using a nebuliser device, while India greenlit a homegrown nasal drop vaccine days later.
With this could not block people from getting infected - and also potentially hamper those who have COVID-19 from spreading it further.
However, the vaccine promoted mucosal antibodies only in a minority of the participants, and the immune responses according to a study published in the journal eBioMedicine.
Recent data from China suggested good results can be achieved by delivery of a similar vaccine deep into the lungs with a more complex nebuliser device. "One possibility is simply that the majority of the nasal spray vaccine ends up being swallowed and destroyed in the stomach - delivery to the lungs could avoid that."
He said that working out exactly why the nasal spray fell short could help researchers discover how to make a future version more effective.
It was "reassuring" that Chinese and Indian nasal vaccines have not shown any serious side effects.
Around 100 different intranasal COVID-19 vaccines are under development worldwide, according to analysis by health data firm Airfinity and Nature last month, with about 20 being tested on humans.
Russia and Iran have also approved nasal vaccines. However, like China and India, they have not published trial data showing that their vaccines stop transmission in a peer-reviewed journal.
21-10-2022, 07:47 PM
https://www.channelnewsasia.com/commenta...er-2706286
Commentary: Could future COVID-19 vaccines work better as nasal sprays?
Scientists are working on vaccines that are delivered as a spray up your nose. These may be better able to prevent COVID-19 infection, says this researcher.
Commentary: Could future COVID-19 vaccines work better as nasal sprays?
Scientists are working on vaccines that are delivered as a spray up your nose. These may be better able to prevent COVID-19 infection, says this researcher.
21-10-2022, 07:55 PM
(21-10-2022, 07:47 PM)Teeth53 Wrote: https://www.channelnewsasia.com/commenta...er-2706286
Commentary: Could future COVID-19 vaccines work better as nasal sprays?
Scientists are working on vaccines that are delivered as a spray up your nose. These may be better able to prevent COVID-19 infection, says this researcher.
Commentary: Could future COVID-19 vaccines work better as nasal sprays?.
Scientists are working on vaccines that are delivered as a spray up your nose. These may be better able to prevent COVID-19 infection, says researcher.
As new waves of Omicron infections continue to hit around the world, it’s becoming clearer that COVID-19 is here to stay. In the years to come, vaccination, both first courses and booster doses will likely remain necessary to brace global communities against the health outcomes wrought by virus.
But what if the current crop of vaccines could be improved? Recent advances in vaccine technology and delivery systems suggest that there could be gains to be made.
In particular, scientists are working on vaccines that activate your “mucosal” immune system, which may be better able to prevent infection with SARS-CoV-2, the virus that causes COVID-19. And rather than being delivered into your arm (intramuscular vaccines), these vaccines could be delivered as a spray up your nose (intranasal vaccines).
NASAL VACCINES STOP THE INFECTION AT ITS SOURCE
Let’s start with some background. SARS-CoV-2 can infect the cells that line the surface of your respiratory tract (commonly referred to as your mucous membranes) all the way from your nose to your lungs. Right across this surface, the virus can damage your cells and provoke an inflammation that leads to further dysfunction both locally and throughout the body.
Vaccines are used to both reduce how much the virus can replicate and control the ensuing inflammation, which is probably the major cause of severe disease and death from COVID-19. Our current vaccines work by presenting a small bit of the virus (the spike protein) as what’s known as an “antigen” to your immune system in your muscle.
The idea is this occurs before a SARS-CoV-2 infection and allows your body to produce antiviral antibodies, which can block the virus from getting inside your cells, as well as T cells, which can help cure those cells that do get infected.
21-10-2022, 08:10 PM
Commentary: Could future COVID-19 vaccines work better as nasal sprays?
But what if the current crop of vaccines could be improved? Recent advances in vaccine technology and delivery systems suggest that there could be gains to be made.
As scientists are working on vaccines that activate your “mucosal” immune system, which may be better able to prevent infection with SARS-CoV-2, the virus that causes COVID-19. And rather than being delivered into your arm (intramuscular vaccines), these vaccines could be delivered as a spray up your nose (intranasal vaccines).
NASAL VACCINES STOP THE INFECTION AT ITS SOURCE. Let’s start with some background. SARS-CoV-2 can infect the cells that line the surface of your respiratory tract (commonly referred to as your mucous membranes) all the way from your nose to your lungs. Right across this surface, the virus can damage your cells and provoke an inflammation that leads to further dysfunction both locally and throughout the body.
Vaccines are used to both reduce how much the virus can replicate and control the ensuing inflammation, which is probably the major cause of severe disease and death from COVID-19. Our current vaccines work by presenting a small bit of the virus (the spike protein) as what’s known as an “antigen” to your immune system in your muscle.
The idea is this occurs before a SARS-CoV-2 infection and allows your body to produce antiviral antibodies, which can block the virus from getting inside your cells, as well as T cells, which can help cure those cells that do get infected.
Why clinical trials in Singapore are a win-win for patients and the economy
Commentary: Will Valneva convince mRNA vaccine sceptics to finally get COVID-19 shots?
Even though it’s initially provided to the muscle in your arm, the vaccine antigen makes its way to your nearby lymph nodes. These are organs which stimulate an immune response in the blood and other fluids that run throughout the body. But what’s often less pronounced following traditional vaccination is the response in mucosal tissues like the gut, lungs or nose. The mucosal immune system is somewhat independent of the systemic one. Given how often these surfaces are exposed to infection or stimuli like dust and pollution, mucosal tissues have their own immune system, composed of specialised antibodies and T cells.
Although standard vaccines do elicit some mucosal protection, the levels aren’t particularly high. But directly presenting the mucosal immune system with vaccine antigen using a delivery method like a nasal spray triggers a significantly more potent mucosal response.
Scientists have often thought that eliciting an immune response in the nose, throat and airways, where typically viruses like SARS-CoV-2 initially enter the body and grow, can result in improved protection compared to intramuscular vaccines – essentially stopping it at the source.
But what if the current crop of vaccines could be improved? Recent advances in vaccine technology and delivery systems suggest that there could be gains to be made.
As scientists are working on vaccines that activate your “mucosal” immune system, which may be better able to prevent infection with SARS-CoV-2, the virus that causes COVID-19. And rather than being delivered into your arm (intramuscular vaccines), these vaccines could be delivered as a spray up your nose (intranasal vaccines).
NASAL VACCINES STOP THE INFECTION AT ITS SOURCE. Let’s start with some background. SARS-CoV-2 can infect the cells that line the surface of your respiratory tract (commonly referred to as your mucous membranes) all the way from your nose to your lungs. Right across this surface, the virus can damage your cells and provoke an inflammation that leads to further dysfunction both locally and throughout the body.
Vaccines are used to both reduce how much the virus can replicate and control the ensuing inflammation, which is probably the major cause of severe disease and death from COVID-19. Our current vaccines work by presenting a small bit of the virus (the spike protein) as what’s known as an “antigen” to your immune system in your muscle.
The idea is this occurs before a SARS-CoV-2 infection and allows your body to produce antiviral antibodies, which can block the virus from getting inside your cells, as well as T cells, which can help cure those cells that do get infected.
Why clinical trials in Singapore are a win-win for patients and the economy
Commentary: Will Valneva convince mRNA vaccine sceptics to finally get COVID-19 shots?
Even though it’s initially provided to the muscle in your arm, the vaccine antigen makes its way to your nearby lymph nodes. These are organs which stimulate an immune response in the blood and other fluids that run throughout the body. But what’s often less pronounced following traditional vaccination is the response in mucosal tissues like the gut, lungs or nose. The mucosal immune system is somewhat independent of the systemic one. Given how often these surfaces are exposed to infection or stimuli like dust and pollution, mucosal tissues have their own immune system, composed of specialised antibodies and T cells.
Although standard vaccines do elicit some mucosal protection, the levels aren’t particularly high. But directly presenting the mucosal immune system with vaccine antigen using a delivery method like a nasal spray triggers a significantly more potent mucosal response.
Scientists have often thought that eliciting an immune response in the nose, throat and airways, where typically viruses like SARS-CoV-2 initially enter the body and grow, can result in improved protection compared to intramuscular vaccines – essentially stopping it at the source.
21-10-2022, 08:11 PM
Good that they continue with COVID zero. It's such a joy to travel on holidays without having to deal with the ahtiong tourists.
21-10-2022, 08:21 PM
CLINICAL TRIALS ARE SHOWING PROMISE
Mucosal vaccines are already in wide use in children for other respiratory pathogens like influenza.
Although the first COVID-19 vaccines to pass clinical trials didn’t specifically target the mucosal immune system, a plethora of new vaccine candidates are being explored in pre-clinical and clinical trials. These include intranasal regimes that could work together with the standard COVID-19 vaccines, but also which could work independently.
In animal trials, mucosal vaccines have shown protective effects. In mice, scientists have observed that intranasal vaccines induce higher levels of protection against infection compared with intramuscular vaccines.
However, don’t know yet whether would be same in people, some preliminary results seem encouraging and candidates have progressed to phase 3 trials.
If proven well in humans, intranasal COVID-19 vaccines. They can be easier to administer, especially to people with a phobia of needles.
They could also provide additional protection. This type of vaccine could be especially useful for people who are most vulnerable to getting very sick with COVID-19, as well as those who tend to spread infection but have a relatively low risk of death, like children and young people.
Mucosal vaccines are already in wide use in children for other respiratory pathogens like influenza.
Although the first COVID-19 vaccines to pass clinical trials didn’t specifically target the mucosal immune system, a plethora of new vaccine candidates are being explored in pre-clinical and clinical trials. These include intranasal regimes that could work together with the standard COVID-19 vaccines, but also which could work independently.
In animal trials, mucosal vaccines have shown protective effects. In mice, scientists have observed that intranasal vaccines induce higher levels of protection against infection compared with intramuscular vaccines.
However, don’t know yet whether would be same in people, some preliminary results seem encouraging and candidates have progressed to phase 3 trials.
If proven well in humans, intranasal COVID-19 vaccines. They can be easier to administer, especially to people with a phobia of needles.
They could also provide additional protection. This type of vaccine could be especially useful for people who are most vulnerable to getting very sick with COVID-19, as well as those who tend to spread infection but have a relatively low risk of death, like children and young people.
21-10-2022, 08:28 PM
(21-10-2022, 08:11 PM)starbugs Wrote: Good that they continue with COVID zero. It's such a joy to travel on holidays without having to deal with the ahtiong tourists.
Before we get to this point, we’ll need significantly more research to support both safety and efficacy.
https://www.channelnewsasia.com/commenta...al-2303051
21-10-2022, 08:36 PM
MAKING VACCINATION EASIER AND NEEDLE-FREE
A nanopatch COVID-19 vaccine, developed by Vaxxas and researchers in Queensland, Australia, has been shown to trigger strong immune responses in animal models, with trials underway in humans.
Another approach, known as an intranasal vaccine, sprays a vaccine up the nose. This would be easier to deliver and it could also build immunity in the right location in our body.
The coronavirus infects us through the lining of the nose, mouth, throat and lungs – a type of sticky tissue that lines body cavities and some organs called mucosa.
Currently, COVID-19 vaccines are delivered into our arm muscle and build antibody levels in our blood and tissue, with some antibody spilling out into the mucosa. Delivering the vaccine directly to the mucosa might be a better approach for preventing COVID-19 infection. This is being trialled with a number of vaccines, including the AstraZeneca vaccine.
A nanopatch COVID-19 vaccine, developed by Vaxxas and researchers in Queensland, Australia, has been shown to trigger strong immune responses in animal models, with trials underway in humans.
Another approach, known as an intranasal vaccine, sprays a vaccine up the nose. This would be easier to deliver and it could also build immunity in the right location in our body.
The coronavirus infects us through the lining of the nose, mouth, throat and lungs – a type of sticky tissue that lines body cavities and some organs called mucosa.
Currently, COVID-19 vaccines are delivered into our arm muscle and build antibody levels in our blood and tissue, with some antibody spilling out into the mucosa. Delivering the vaccine directly to the mucosa might be a better approach for preventing COVID-19 infection. This is being trialled with a number of vaccines, including the AstraZeneca vaccine.
21-10-2022, 08:41 PM
Sinkapore also cannot move on mah. Restrictions removed after 5 days says wanna put back. Jokers
21-10-2022, 08:42 PM
(21-10-2022, 05:12 PM)sgbuffett Wrote: https://www.channelnewsasia.com/commenta...ut-3017096
Last month China became the first country to approve a needle-free COVID-19 vaccine, an aerosolised mist inhaled through the nose and mouth using a nebuliser device, while India greenlit a homegrown nasal drop vaccine days later.
With this could not block people from getting infected - and also potentially hamper those who have COVID-19 from spreading it further.
21-10-2022, 10:44 PM
support covid zero…please close for 10 more years
22-10-2022, 12:12 AM
(21-10-2022, 08:42 PM)Teeth53 Wrote: Last month China became the first country to approve a needle-free COVID-19 vaccine,India also claimed to have approved needle free vaccine. Is there any scientific report and WHO’s approval? How come Singapore not using?
Omi.. Thank you for bumping up the message.
22-10-2022, 08:20 AM
What a pity.. real still good after opening.
22-10-2022, 11:57 AM
(21-10-2022, 06:46 PM)webinarian Wrote:Those who against Xi policies, need to restudy their language
US famous Harvard U did a ten years' study of support and popularity of Gov among the people in China, they found their support rate generally are between 80 to 95%.
Do you see such support and satisfaction in western govs like Biden, Truss and Macron?
Breakthrough Research Shows Growing Public Satisfaction with Chinese Government (asiapacific.ca)
Understanding CCP Resilience: Surveying Chinese Public Opinion Through Time | Ash Center (harvard.edu)
https://yt3.ggpht.com/P9-G647GCs2NGxHQk1...s800-nd-v1
22-10-2022, 12:11 PM
The president takes what is appropriate measure to protect its citizen well being thats represent the heartbeat of the country according to his belief which is the best at this moment . Nothing to to be ashamed of.
We should be thankful he make this effort to slow down the spreading. If not our country may be eliminated by the virus. What did the western country do to prevent from spreading?
We should be thankful he make this effort to slow down the spreading. If not our country may be eliminated by the virus. What did the western country do to prevent from spreading?
16-04-2023, 12:51 PM
(22-10-2022, 12:11 PM)Ernesto Wrote: The president takes what is appropriate measure to protect its citizen well being thats represent the heartbeat of the country according to his belief which is the best at this moment . Nothing to to be ashamed of.
We should be thankful he make this effort to slow down the spreading. If not our country may be eliminated by the virus. What did the western country do to prevent from spreading?
TS gonna lover this.. and silenced by his own thread...
Bloomberg (21 Mar 2023)...
4 months after moving away from Zero-COVID...China is reopening — but more cautiously than other places, especially those that imposed fewer restrictions.. “Compared with the US, China's post-Covid recovery is slower,” he said. “The US had revenge spending that China does not have. Consumer confidence in the reopening phase of the US was much higher and the government gave out a lot of subsidies. China has neither.”
“China's recovery is just beginning.”
https://www.bloomberg.com/news/features/...on-remains
You've got friendly neighbours? Grow Up! - 李光耀 2013
16-04-2023, 02:42 PM
(16-04-2023, 12:51 PM)Manthink Wrote: TS gonna lover this.. and silenced by his own thread...You didn't realise that TS is always wrong?
Bloomberg (21 Mar 2023)...
4 months after moving away from Zero-COVID...China is reopening — but more cautiously than other places, especially those that imposed fewer restrictions.. “Compared with the US, China's post-Covid recovery is slower,” he said. “The US had revenge spending that China does not have. Consumer confidence in the reopening phase of the US was much higher and the government gave out a lot of subsidies. China has neither.”
“China's recovery is just beginning.”
https://www.bloomberg.com/news/features/...on-remains
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