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14-10-2022, 01:04 PM
Four variant-containing mRNA vaccines which include Omicron subvariants BA.1 or BA.4/5 in combination with the ancestral virus have been authorised for use as booster doses.
The vaccines adapted to the globally-dominant variant may offer only a "minute incremental benefit", the WHO's Strategic Advisory Group of Experts on Immunisation (SAGE) said.
"It's a relatively modest effect which we can see in the laboratory," he said.
"What we cannot do is to relate these laboratory measures with an increase in clinical protection," because such effectiveness data is not yet available.
"Since our recommendations should be really grounded in evidence, we cannot issue a preferential statement for these vaccines," Hombach said.
https://medicalxpress.com/news/2022-10-p...perts.html
The vaccines adapted to the globally-dominant variant may offer only a "minute incremental benefit", the WHO's Strategic Advisory Group of Experts on Immunisation (SAGE) said.
"It's a relatively modest effect which we can see in the laboratory," he said.
"What we cannot do is to relate these laboratory measures with an increase in clinical protection," because such effectiveness data is not yet available.
"Since our recommendations should be really grounded in evidence, we cannot issue a preferential statement for these vaccines," Hombach said.
https://medicalxpress.com/news/2022-10-p...perts.html
