SG Talk

Full Version: Explained: What is the very rare Bombay blood group?
You're currently viewing a stripped down version of our content. View the full version with proper formatting.
I came across this blood group while watching the 2008 HK TV series 法证先锋2 (Forensic Heroes Season 2). Interesting info so I am posting it here.


Written by Tabassum Barnagarwala | Mumbai |
Updated: September 11, 2019 8:08:43 am


......

The rare, Bombay blood group was first discovered in Mumbai (then Bombay) in 1952 by Dr Y M Bhende. Each red blood cell has antigen over its surface, which helps determine which group it belongs to. The Bombay blood group, also called hh, is deficient in expressing antigen H, meaning the RBC has no antigen H. For instance, in the AB blood group, both antigens A and B are found. A will have A antigens; B will have B antigens. In hh, there are no A or B antigens.

......

Globally, the hh blood type has an incidence of one in four million. It has a higher incidence in South Asia; in India, one in 7,600 to 10,000 are born with this type.

Dr Arun Thorat, in-charge of Maharashtra State Blood Transfusion Council, said this blood type is more common in South Asia than anywhere else because of inbreeding and close community marriages.

......

Often the hh blood group is confused with the O group. The difference is that the O group has Antigen H, while the hh group does not.

If anyone lacks Antigen H, it does not mean he or she suffers from poor immunity or may be more prone to diseases. Their counts for haemoglobin, platelets, white blood cells and red blood cells are similar to the count of others based on their health index. Because of rarity, however, they do face problems during blood transfusion.

......

Rejection may occur if they receive blood from A, B, AB or O blood group. In contrast, hh blood group can donate their blood to ABO blood types.

......

This group is generally not stored in blood banks, mainly because it is rare and the shelf life of blood is 35-42 days. So, whenever there is a demand for a Bombay blood group patient, a donor is required very urgently. Sometimes, facilities need to be created for transporting the donated blood from one city to another.


https://indianexpress.com/article/explai...r-5984653/