21-12-2021, 12:05 PM
The company said it would "amend" the trial to add a third dose.
Early tests had indicated that this small dose would produce a strong immune response in the children and minimize the risk of side effects.
But the interim data -- which the independent Data and Safety Monitoring Board can see without giving details to the company or investigators -- indicates this small dose regimen did not produce the expected immune response in the 2- to 5-year-olds.
The company will also test third doses in older children, who do not yet have authorization for booster doses of vaccine. Kids ages 5 to 11 and 12 to 15 will get full-dose third shots in the trials.
The changes probably mean a delay in authorization for vaccines for younger children, Dr. Anthony Fauci said.
https://edition.cnn.com/2021/12/17/healt...index.html
Early tests had indicated that this small dose would produce a strong immune response in the children and minimize the risk of side effects.
But the interim data -- which the independent Data and Safety Monitoring Board can see without giving details to the company or investigators -- indicates this small dose regimen did not produce the expected immune response in the 2- to 5-year-olds.
The company will also test third doses in older children, who do not yet have authorization for booster doses of vaccine. Kids ages 5 to 11 and 12 to 15 will get full-dose third shots in the trials.
The changes probably mean a delay in authorization for vaccines for younger children, Dr. Anthony Fauci said.
https://edition.cnn.com/2021/12/17/healt...index.html