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Full Version: US: 4th Dose might save thousands of lives if a new coronavirus wave hit
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After fraught discussions, officials decided that another shot might save thousands of lives if a new coronavirus wave hit before the fall. The F.D.A. could authorize the boosters next week.

Major uncertainties have complicated the decision, including how long the protection from a second booster would last, how to explain the plan to the public and even whether the overall goal is to shield Americans from severe disease or from less serious infections as well, since they could lead to long Covid.

Much depends on when the next wave of Covid infections will hit, and how hard. Should the nation be hit by a virulent surge in the next few months, offering a second booster now for older Americans could arguably save thousands of lives and prevent tens of thousands of hospitalizations.

Many experts argue that the existing coronavirus vaccines need to be modified because the virus’s variants are diminishing their power; the question is how to reconfigure them. A surge in the fall is considered highly likely, whether it comes in the form of the Omicron variant, a subvariant like BA.2 or a new lineage entirely.

If all goes well, that would allow enough time to produce new doses before the fall. One major hitch is that the Biden administration says it does not have the money it needs to reserve its place in line by paying vaccine manufacturers for doses in advance.

Besides the C.D.C., Britain and Israel have put out data on the waning effectiveness of booster shots. 

The latest report by Britain’s health security agency states that effectiveness against symptomatic infection drops to between 25 percent and 40 percent 15 weeks or longer after a booster dose of either Pfizer or Moderna.

https://www.nytimes.com/2022/03/25/us/po...icans.html