Do Vaccines Really Reduce Hospitalization and Mortality?

Do Vaccines Really Reduce Hospitalization and Mortality? - Printable Version

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Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1325243/full

https://www.youtube.com/watch?v=uNaRkHEUIy8

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

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Our additional survival analyses demonstrated that the NVax patients admitted post-COVID-19 vaccine introduction had increased risk of mortality compared to those admitted pre-vaccine introduction (Supplementary Figure 2A). This could result from different dominant variants circulating during these different time periods (e.g. pre-Delta and Delta variants). However, Vax patients had significantly higher risk of mortality compared to both NVax groups (Supplementary Figures 2B, C).

In an attempt to control our observation, we assessed a cohort of 40 patients admitted to the hospital with non-COVID ARF. Mortality rates did not differ significantly between Vax (27%) and NVax (36%) patients (Supplementary Table S1). However, the number of patients in this cohort was also low, thereby limiting our ability to make conclusions.

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

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To evaluate the role of SARS-CoV-2/CCCoV-specific Abs in severe COVID-19 pathogenesis and immunity, we analyzed plasma levels of SARS-CoV-2/CCCoV IgG, IgA and IgM Abs of the SARS-CoV-2 infected patients. Assessment of Ab levels between these patient populations revealed some, but not definitive differences that stratified outcome. The SARS-CoV-2-S specific IgG/IgM Abs levels/titers of the younger Vax patients (19-49 years) were consistently higher than those of the NVax patients (Figure 3A). Further, non-survivors had lower SARS-CoV-2 N/CCCoV N Ab levels/titer compared to those patients who survived, and this trend was more pronounced in the Vax group (Figures 3B and Supplementary Figure 3). Additionally, the SARS-CoV-2-N specific IgG/IgA/IgM Abs titers of the NVax patients were significantly higher than those of the Vax patients (Figure 3C). Interestingly, NVax patients with comorbidities had higher SARS-CoV-2 specific Ab levels compared to their Vax counterparts (Supplementary Figure 3), suggesting that the presence of comorbidities was not the sole contributing factor to the decreased Ab response.

Thus, contrary to our expectations, we observed decreased Ab levels in the Vax compared to the NVax group

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

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Interestingly, mortality among Vax patients in this cohort was 70% compared with 37% in the NVax group, and overall survival rate was ~2 times higher in the NVax patients (p=0.0086, Supplementary Table 1).

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

We next tested total IgG4 levels given emerging evidence that this isotype may have a role in the development of immunotolerance, and the association between COVID-19 mRNA vaccines and plasma IgG4 increases (7). Indeed, there was a trend for higher concentrations of total IgG4 Abs in the Vax vs NVax COVID-19 patients in week 3 (Supplementary Figure 4).

Comorbidities and age are the known contributors to increased mortality among COVID-19 patients (5). Nonetheless, in our study, mortality remained significantly higher in the Vax patients even after adjustment for CCI, suggesting there are other risk factors in vaccinated patients.

This led us to investigate the immunological basis for our clinical observations. We observed reduced SARS-CoV-2-reactive Ab levels in Vax non-survivors. As a possible explanation for this observation, recent studies have shown that mRNA (but not vector-based) vaccine-associated increases in SARS-CoV-2 S-specific IgG4 levels vaccines did not contribute to increased protection (7, 8, 15). In contrast, they were thought to suppress antiviral immune responses, promoting immune tolerance and, possibly, unrestricted SARS-CoV-2 replication (7, 8, 16). In our study, the observed trend for increased total IgG4 concentration in week 3 for Vax patients may explain the reduced protective Ab responses. Of significance, clinical onset of IgG4-related non-infectious diseases is most often recorded in patients older than 50 years, which further corroborates our findings of increased mortality in this age group (16, 17).

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

need some advice how to wash the blood off yer dirty hands? Tongue

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - watchfirst9 - 07-06-2024

(07-06-2024, 05:20 PM)Geneco Wrote: need some advice how to wash the blood off yer dirty hands?

PPP never send the above report to MOH.
else MOH may drop sms include statement can vax 3 months after infection

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

(07-06-2024, 05:36 PM)watchfirst9 Wrote: PPP never send the above report to MOH.
else MOH may drop sms include statement can vax 3 months after infection

Won't drop won't drop... Tongue

Must meh meh pak latest mRNA jab lolololol Tongue

Benefits outweighs the risk Tongue

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - watchfirst9 - 07-06-2024

(07-06-2024, 05:38 PM)Geneco Wrote: Won't drop won't drop...

Must meh meh pak latest mRNA jab lolololol

Benefits outweighs the risk

ok ok go 怕 latest mRNA jab Rolleyes

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - factuup - 07-06-2024

JIUHUSAI GENEDOG PRETENDING TO TOK LIKE HE CARES ABOUT INNOCENTS AND WTF 'BLOOD ON THEIR HANDS' ETC.

GOT SGTOKERS SO DAFT BELIEVE GENEDOG ISH A SAINT? BY NOW WE STILL DONNO WHAT JHK SHIT STIRRERS AT WORK ARE LIKE?

MORE LIKELY THIS JHK GENEDOG EVERYDAY PRAY MORE SG VAXXED PPL DIE SO AS TO 'PROVE' HE IS RIGHT. IT'S ALL ABOUT HIS LITTLE EGO IN LITTLE FORUMS LOL!

JHK PREESH TOK MORE ABOUT INNOCENTS I'M SO TOUCHED Laughing

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - sporeguy - 07-06-2024

(07-06-2024, 05:20 PM)Geneco Wrote: need some advice how to wash the blood off yer dirty hands?

Many are taking a combination of Quercetin & Bromelain vit C, D and Zinc to purge mRNA from the body.

https://www.patrickholford.com/shorteninglongcovid/

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - EvertonDiehard - 07-06-2024

Apart from increased instances of unexplained deaths after the introduction of Covid-19 vaccinations, the fact that the vaccinated still got infected after getting jabbed and wearing masks, I conclude that it is safer not to be vaccinated. I was infected with Covid twice during the period that I underwent 3 jabs. Ever since refusing further jabs due to heart palpitations following my third shot, I have not been infected.

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

Need some advice on how to continue shilling for mRNA vax and suppress/hide other life saving information costing the lives and livelihoods of innocents... Tongue

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

(07-06-2024, 05:43 PM)watchfirst9 Wrote: ok ok go 怕 latest mRNA jab

Not scared not scared! Tongue

4000000% safe and effective like thaliodamide... Tongue

Their psychopathic and narcissistic mouths say very safe, covid very dangerous to maintain their face, but body very honest as all dunch dare to GPGT their latest mRNA jab as recommended by MOH lololololol... Tongue

Need some advice why ish this so? Tongue

RE: Do Vaccines Really Reduce Hospitalization and Mortality? - Geneco - 07-06-2024

(07-06-2024, 06:42 PM)sporeguy Wrote: Many are taking a combination of Quercetin & Bromelain vit C, D and Zinc to purge mRNA from the body.

https://www.patrickholford.com/shorteninglongcovid/

cannot purge cannot purge! Tongue

purging it ish limiting the capabilities of mRNA tech via papagranda! Tongue