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+--- Thread: NUS,A*Star researchers develop sensor that can detect cholesterol & glucose from skin (/Thread-NUS-A-Star-researchers-develop-sensor-that-can-detect-cholesterol-glucose-from-skin)
NUS,A*Star researchers develop sensor that can detect cholesterol & glucose from skin - Levin - 19-08-2024
https://www.straitstimes.com/singapore/health/nus-astar-researchers-develop-sensor-that-can-detect-cholesterol-and-glucose-from-skin
RE: NUS,A*Star researchers develop sensor that can detect cholesterol & glucose from skin - Tee tiong huat - 19-08-2024
NUS, A*Star researchers develop sensor that can detect cholesterol and glucose from skin Dr Yang Le, principal scientist at A*Star, with the wearable, stretchable hydrogel-based sensor, which can detect biomarkers such as cholesterol, lactate and glucose.
SINGAPORE - A new, non-invasive method may do away with the need to draw blood for testing blood glucose and cholesterol levels. Researchers from the National University of Singapore (NUS) and the Agency for Science, Technology and Research (A*Star) have developed a stretchable, hydrogel-based sensor that can detect such biomarkers in a solid state on the skin. The technology could be used in wearables for purposes such as chronic disease management and remote patient monitoring.
The team’s findings published in the scientific journal Nature Materials in June. While traditional methods of monitoring biomarkers in fluids such as blood, urine and sweat are effective, they come with hurdles that can impede the early diagnosis and treatment of diseases. Blood tests, for example, can be invasive and inconvenient, while sweat can be difficult to induce in inactive people. The researchers noted such challenges do not apply to solid-state epidermal biomarkers – which include cholesterol and lactate – that are found in the stratum corneum, the outermost layer of the skin. Such biomarkers have shown strong correlations with diseases such as cardiovascular disease and diabetes.
Outside of some scattered literature, these correlations have been overlooked for decades, said Assistant Professor Liu Yuxin from the NUS Institute for Health Innovation & Technology. Prof Liu, who is one of the leads for study, said solid electrodes placed on skin, used in conventional monitors, do not allow for electrochemical sensing of these biomarkers.Instead of electrodes, the sensor developed by researchers uses hydrogels, which dissolve diffuse solid-state epidermal biomarkers that then undergo electrochemical reactions catalysed by enzymes.
This results in the transfer of electrons to an electronically conductive hydrogel, which can then be read by a flexible printed circuit board connected to the sensor. The circuit board is able to wirelessly transmit the relevant physiological data to a user, who can use the data to monitor a patient’s health.
Dr Yang Le, principal scientist and head of the sensors and flexible electronics department at the A*Star Institute of Materials Research and Engineering, said the sensor is possibly the first such device that is able to monitor biomarkers on dry skin.
“The stretchable design enhances comfort and accuracy as well, by adapting to our skin’s natural elasticity. This innovation can change the way we approach health and lifestyle monitoring, particularly for those living with chronic conditions requiring constant health monitoring,” said Dr Yang, who is the study’s other lead.
RE: NUS,A*Star researchers develop sensor that can detect cholesterol & glucose from skin - klat - 19-08-2024
It is an alternative way of sensing.
What is so great?
RE: NUS,A*Star researchers develop sensor that can detect cholesterol & glucose from skin - Levin - 19-08-2024
(19-08-2024, 02:39 PM)klat Wrote: It is an alternative way of sensing.
What is so great?
?? As stated in the report, convenient and non-invasive.