China's potential mRNA Covid vaccine weaker against Omicron-study - Printable Version
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China's potential mRNA Covid vaccine weaker against Omicron-study - theold - 15-02-2022
A Chinese mRNA vaccine candidate showed a sharp drop in neutralizing antibody activity against Omicron than against the non-mutated coronavirus in a small study, but a booster readily induced antibody production in animal tests, a research paper said.
https://www.thestandard.com.hk/breaking-news/section/3/187183/China's-potential-mRNA-Covid-vaccine-weaker-against-Omicron-study%C2%A0
The neutralizing antibody level against Omicron showed a 47-fold reduction compared with the level against a "wild-type" that contains no major mutations, said the paper published on Monday.
But in animal tests, a third dose, given about nine months after the second shot, readily induced the production of neutralizing antibodies against Omicron and a wild-type strain, it said.
"Our data presented here clearly demonstrate that a third dose of ARCoV would probably lead to a sharp increase in neutralization antibodies not only against the WT (wild type) SARS-CoV-2 but also the newly Omicron variant," the study said.