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+--- Thread: The Covid-19 treatment given to Trump has been cleared in US, India and, now, UK (/Thread-The-Covid-19-treatment-given-to-Trump-has-been-cleared-in-US-India-and-now-UK)
The Covid-19 treatment given to Trump has been cleared in US, India and, now, UK - theold - 15-09-2021
The treatment contains two mAbs: casirivimab and imdevimab. They are designed to stop the coronavirus attaching to ACE2, a receptor found on the surface of human cells in the respiratory tract.
Two Vectors
One of the mAbs is derived from a Covid-fighting immune cell taken from a human survivor of the disease.
The other was produced in a mouse genetically modified to have a human immune system.
The advantage of combining the two is that they target two different parts of the spike protein, many of which protrude from the coronavirus – these are what it uses to bind with ACE2.
Using both reduces the chance of the virus escaping from the immune system.
https://scroll.in/article/1004035/explainer-the-covid-19-treatment-given-to-trump-has-authorisation-in-us-india-and-now-uk
RE: The Covid-19 treatment given to Trump has been cleared in US, India and, now, UK - theold - 15-09-2021
US demand for COVID-19 antibody treatments rising fast
The cost of the monoclonal antibody treatments for COVID-19 remains a thorny issue. REGEN-COV has a list price of about $1,250 per dose, while sotrovimab is more than $2,000 per dose, although Regeneron’s product is free to patients as the bill is paid by the federal government.
GSK has a co-pay programme for commercial patients and, due to previous government relief bills, patients with Medicare and Medicaid, and the uninsured, don’t have to pay to get the treatment.
https://www.pmlive.com/pharma_news/us_demand_for_covid-19_antibody_treatments_rising_fast_1376021