Posts: 26,901
   
Threads: 19,080
    
Likes Received: 2,259 in 2,101 posts
Likes Given: 24
17-12-2021, 08:00 AM
Novavax's vaccines are expected to cause less adverse and less severe reaction compared to both the mRNA vaccines and the J&J vaccine.
Additionally, Novavax vaccine might prove to be a better option for children because of NVX-COV2373's higher safety profile.
They only require storage temperatures of 2° to 8°, which makes the logistics of shipping NVX-CoV2373 to warm weather climates a far easier task.
https://static.seekingalpha.com/uploads/...156946.jpg
https://seekingalpha.com/article/4475509...enues-2022
Posts: 5,440
   
Threads: 76
    
Likes Received: 823 in 763 posts
Likes Given: 256
(17-12-2021, 08:00 AM)theold Wrote: Novavax's vaccines are expected to cause less adverse and less severe reaction compared to both the mRNA vaccines and the J&J vaccine.
Additionally, Novavax vaccine might prove to be a better option for children because of NVX-COV2373's higher safety profile.
They only require storage temperatures of 2° to 8°, which makes the logistics of shipping NVX-CoV2373 to warm weather climates a far easier task.
https://static.seekingalpha.com/uploads/...156946.jpg
https://seekingalpha.com/article/4475509...enues-2022
Maybe less protein spike being attach to cell.
SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V ...
https://www.ncbi.nlm.nih.gov › pmc › articles › PMC8538446
Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.
mRNA create only spikes and many fold more.
Posts: 26,901
   
Threads: 19,080
    
Likes Received: 2,259 in 2,101 posts
Likes Given: 24
While Valneva takes the whole virus, Novavax takes a slice(sub-units) of the virus.
Posts: 26,901
   
Threads: 19,080
    
Likes Received: 2,259 in 2,101 posts
Likes Given: 24
The Novavax vaccine uses a telltale piece of the coronavirus: the notorious spike protein.
"Unlike mRNA vaccines, the spike protein is already premade in the Novavax vaccine. It's a shortcut," explains Dr. Florescu. "All the synthesis happens outside the body and we just give the end product: the spike protein."
Like other COVID-19 vaccines, Novavax does not cause COVID-19 infection. It can't get you sick.
Researchers select the desired genes that create certain SARS-CoV-2 antigens (spike protein).
Researchers put the genes into a baculovirus, an insect virus.
The baculovirus infects moth cells and replicates inside them.
These moth cells create lots of spike proteins.
Researchers extract and purify the spike proteins.