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05-01-2022, 09:39 PM
It is not sustainable to give COVID-19 booster shots every three to six months in the long term.
https://www.koreatimes.co.kr/www/world/2...21701.html
(This post was last modified: 05-01-2022, 09:40 PM by
theold.)
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Time to try single dose, that can also induce mucosal protection method...
https://pubmed.ncbi.nlm.nih.gov/32931734/
Intramuscular dosing of ChAd-SARS-CoV-2-S induces robust systemic humoral and cell-mediated immune responses and protects against lung infection, inflammation, and pathology but does not confer sterilizing immunity, as evidenced by detection of viral RNA and induction of anti-nucleoprotein antibodies after SARS-CoV-2 challenge. In contrast, a single intranasal dose of ChAd-SARS-CoV-2-S induces high levels of neutralizing antibodies, promotes systemic and mucosal immunoglobulin A (IgA) and T cell responses, and almost entirely prevents SARS-CoV-2 infection in both the upper and lower respiratory tracts