Decongestant ingredient in popular products does not work, FDA concludes
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Advisory panel reviewed studies of phenylephrine, an active ingredient in Benadryl, Mucinex, Sudafed PE and Tylenol

An advisory panel spent two days looking at studies of phenylephrine, an active ingredient in well-known medicines including Benadryl, Mucinex, Sudafed PE and Tylenol, and reported to the FDA that it is no more effective than a placebo.

Concerns over its effectiveness surfaced publicly in 2007, when University of Florida pharmacists urged the FDA to take the drug off the market. “The bottom line is quality research has told the true story of phenylephrine,” Dr Leslie Hendeles, one of the original research group, and now professor emeritus at the university, told the Times on Tuesday.

The Consumer Healthcare Products Association (CHPA), which represents drug manufacturers, argued that the ingredient was effective, citing a survey that claimed 83% of Americans found it helped symptoms, and insisting it played “a critical role in public health”.

https://www.theguardian.com/us-news/2023...nylephrine
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