Long COVID:Lost connections between cells in the brain may explain cognitive symptoms
#1
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Some people with long COVID complain of “brain fog”, which includes a wide variety of cognitive symptoms affecting memory, concentration, sleep and speech.

In a recent study, we created brain organoids a little bigger than a pinhead and infected them with SARS-CoV-2, the virus that causes COVID-19.

In these organoids, we found that an excessive number of synapses (the connections between brain cells) were eliminated – more than you would expect to see in a normal brain.


In other research, we’ve observed that an antibiotic called minocycline can reduce the degree to which microglia prune synapses in a dish. So we want to see if this drug can help in our brain organoid models following SARS-CoV-2 infection.

https://theconversation.com/long-covid-h...oms-192702
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#2

ya spike proteins have crossed the Blood-brain barrier
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