Treating a type 2 diabetic patient with impaired pancreatic islet function
#1

The patient was a 59-year-old man with a 25-year history of T2D who developed end-stage diabetic nephropathy and underwent kidney transplantation in June of 2017 and displayed poor glycemic control since November of 2019, characterized by blood glucose level ranging from 3.66–14.60 mmol/L, mean amplitude of glycemic excursion (MAGE) of 5.54 mmol/L, the time-in-the-tight-target-range (TITR, 3.9–7.8 mM) of 56.7%, with daily hyperglycemic events (> 10.0 mmol/L) of 0.7/d and hypoglycemic events (< 3.9 mmol/L) of 0.3/d (Supplementary Table S1). 

Due to the major concerns of hypoglycemia and the detrimental effect of poor glycemic control on the long-term survival of the donor kidney, the patient agreed to pursue transplantation with autologous E-islets.


https://www.nature.com/articles/s41421-024-00662-3
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#2

The World Health Organization (WHO) estimates that 90 percent of people around the world who have diabetes have type 2.
https://www.healthline.com/health/type-2...statistics

Type 1 diabetes affects just 5% of all people with diabetes. It is usually diagnosed in children and young adults.
https://www.singhealth.com.sg/patient-ca...g%20adults.
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