![](https://i.imgur.com/CLvY2jA.png")
July 1, 2022 -- A study funded by the National Institutes of Health (NIH) has shown that a new universal flu vaccine offers broad protection against different strains and subtypes of influenza A virus infections.
Their published findings in the journal npj Vaccines showed that M2e-stalk protein vaccination induced broad protection against different influenza virus strains and subtypes by universal vaccine-mediated immunity in adult and aged mice.
The candidate vaccine, BPL-1357, is a whole-virus vaccine made up of four strains of non-infectious, chemically inactivated, low-pathogenicity avian flu virus.
An animal study, led by NIAID investigator Dr. Jeffery Taubenberger, PhD, and posted online as a preprint, found that all mice receiving two doses of BPL-1357 vaccine delivered either intramuscularly or intranasally survived later exposure to lethal doses of each of six different influenza virus strains, including subtypes that were not included in the vaccine.
NIH reports that similar results were obtained in challenge experiments in which ferrets were vaccinated with BPL-1357.
https://www.scienceboard.net/index.aspx?sec=ser&sub=def&pag=dis&ItemID=4418
Their published findings in the journal npj Vaccines showed that M2e-stalk protein vaccination induced broad protection against different influenza virus strains and subtypes by universal vaccine-mediated immunity in adult and aged mice.
The candidate vaccine, BPL-1357, is a whole-virus vaccine made up of four strains of non-infectious, chemically inactivated, low-pathogenicity avian flu virus.
An animal study, led by NIAID investigator Dr. Jeffery Taubenberger, PhD, and posted online as a preprint, found that all mice receiving two doses of BPL-1357 vaccine delivered either intramuscularly or intranasally survived later exposure to lethal doses of each of six different influenza virus strains, including subtypes that were not included in the vaccine.
NIH reports that similar results were obtained in challenge experiments in which ferrets were vaccinated with BPL-1357.
https://www.scienceboard.net/index.aspx?sec=ser&sub=def&pag=dis&ItemID=4418
