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The available scientific information as well as the widely reported cases of vaccine breakthrough cases is sufficient for a conclusion that the mRNA vaccines are no longer effective as primary vaccination in a two-dose prime-boost combination. The German study also indicated that a booster shot for a "triple" vaccination is not effective.
Effectiveness of 70 to 75% in the early period after a booster dose seems to say the same as after the 2nd dose, some early efficacy after the booster, then waning rapidly after a few weeks.
The German study showed that a third dose may be as ineffective as two doses. There is no clinical study data to indicate that a booster shot will in fact make any difference to protection for a period longer than a couple of weeks.
The UK study indicated that protection in the first 2-9 weeks were acceptable but could drop below 50% as early as after 2 weeks and by week 15 it was down to 34% to 37% effective. Boosters would probably follow the same trajectory.
Expecting people to get a booster shot every 2-3 months will not gain public acceptance and the vaccine must be considered a failure against Omicron if its protection wanes below 50% after as little as 2 weeks.
https://seekingalpha.com/article/4475389...nd-novavax
Effectiveness of 70 to 75% in the early period after a booster dose seems to say the same as after the 2nd dose, some early efficacy after the booster, then waning rapidly after a few weeks.
The German study showed that a third dose may be as ineffective as two doses. There is no clinical study data to indicate that a booster shot will in fact make any difference to protection for a period longer than a couple of weeks.
The UK study indicated that protection in the first 2-9 weeks were acceptable but could drop below 50% as early as after 2 weeks and by week 15 it was down to 34% to 37% effective. Boosters would probably follow the same trajectory.
Expecting people to get a booster shot every 2-3 months will not gain public acceptance and the vaccine must be considered a failure against Omicron if its protection wanes below 50% after as little as 2 weeks.
https://seekingalpha.com/article/4475389...nd-novavax
