[theold]

T-cells, which can “remember” past infections and kill pathogens if they reappear, are thought to have a big influence on how long people remain resistant to infection and disease. They come in several different types, including killer T-cells, helper T-cells and memory T-cells. B-cells, another essential type of white blood cell, produce antibodies.

The findings are likely to alleviate some of the concerns about new strains outsmarting the existing crop of vaccines.


https://www.ft.com/content/16a2bea8-457e...b31ddd89c0

[theold]

https://www.mountelizabeth.com.sg/images...=635da11_2

https://www.mountelizabeth.com.sg/health...e-efficacy

[dynamite]

If this is the case, why did vaccine efficiency wane off very significantly from 6 months onwards?

[theold]

Where to obtain the Sinopharm vaccine
As part of the fight against COVID-19, IHH Healthcare Singapore has brought in the Sinopharm vaccine. The vaccine is priced at S$99 for 2 doses, inclusive of GST.

Please note that we are currently out of stock for the Sinopharm vaccine. Stay tuned for more information as we work to replenish supplies.

https://www.mountelizabeth.com.sg/?ef_id...vD_BwE:G:s&gclid=EAIaIQobChMI_d6J7fTh8gIV7JhmAh0CFQPgEAAYASAAEgJtCvD_BwE

[theold]

If this is the case, why did vaccine efficiency wane off very significantly from 6 months onwards?

One is the anti-bodies while the the other is the memory. For inactivated, it is more about memory. Vaccinations start when one is very young.

[dynamite]

One is the anti-bodies while the the other is the memory. For inactivated it is more about memory. Vaccinations start when one is very young.

Take both. And one more, subunit type also.

[RiseofAsia]

T- cell is 2nd line of defence.

[RiseofAsia]

https://youtu.be/lXfEK8G8CUI

[dynamite]

T- cell is 2nd line of defence.

Natural killer cells

[Sticw]

If this is the case, why did vaccine efficiency wane off very significantly from 6 months onwards?

That puzzled me when it was first reported in early days of covid situation. Body T cells are supposed to remember, it's not can or cannot, the T cell job in the human bio is for that recalling so they can signal to manufacture the right defense cells. 

What's strange about this whole covid is that they reported that T cell never remember or can forget covid. Which makes me wonder if covid is so heavily modified such that the body doesn't recognize the code as it's illogical or unnatural...

[lvlrsSTI]

on the other hand, viruses like Covid are also very smart, they know how to get around with the vaccines through endless mutation.

[sgxin]

That puzzled me when it was first reported in early days of covid situation. Body T cells are supposed to remember, it's not can or cannot, the T cell job in the human bio is for that recalling so they can signal to manufacture the right defense cells. 

What's strange about this whole covid is that they reported that T cell never remember or can forget covid. Which makes me wonder if covid is so heavily modified such that the body doesn't recognize the code as it's illogical or unnatural...

I believe what was reported previously is that the Covid antibodies will drop fast after infection and not the T cell memory.
Sinov 3rd dose study (below) seems to confirm that the latter is still present.

As for the Covid antibodies, I am still wondering if too high level of it will be detrimental to one's health cos the ACE2 receptor on our cells must be serving some biological functions. A high level of the antibodies will logically block the naturally occuring entity (exosomes?) from entering the cell to carry out such functions (detox?).
And could the crippling of the detox functions by the antibodies increase risk of certain illnesses (e.g someone posted on hwz of the Korean hypothesis of leukemia)?

Sinovac booster shot gives big increase in neutralizing antibodies: study
https://www.globaltimes.cn/page/202108/1231014.shtml

Neutralizing antibody titers declined substantially six months after two doses of CoronaVac among older adults, according to the study.

The participants were given a third dose of 3μg, 6μg or placebo eight months following the second dose. An additional dose of 1.5μg was added to the study.

The results indicate that in all 1.5μg, 3μg, and 6μg dose vaccine groups, the level of neutralizing antibodies increased significantly on day seven after the third dose of the vaccine.

In the group of participants who received the 3μg vaccine, which is approved for emergency use, the geometric mean titer (GMT) of serum neutralizing antibodies increased to 305 on day seven after the third dose, an approximately seven-fold increase compared to the levels at day 28 after the second dose.

Concerns over people reportedly getting leukemia after being vaccinated against COVID-19 (Pfizer) in Korea
https://forums.hardwarezone.com.sg/threa...942/page-3